Tulaga maualuga Doxycycline HCl CAS 24390-14-5 ma le tau sili ona lelei
Fa'amatalaga o oloa
E ala i le toe faʻafeiloaʻi i le talipupuni i luga o le 30S subunit o le ribosome siama, doxycyclin faʻalavelave i le faʻavaeina o le ribosome faʻalavelave i le va o le tRNA ma le mRNA, ma taofia ai le filifili peptide mai le faʻaumiumi o le protein synthesis, ina ia vave faʻalavelaveina le tuputupu aʻe ma le toe gaosia o siama. E mafai e le Doxycycline ona fa'alavelaveina siama kalama-lelei ma le kalama-leaga, ma e fa'afeagai ma le oxytetracycline ma aureomycin.
Afa'asoa
Mo le togafitia o faʻamaʻi pipisi e mafua mai i siama gram-positive ma gram-negative ma mycoplasma, e pei ole porcine mycoplasma, colibacillosis, salmonellosis, pasteurellosis, ma isi.
Tali leaga
O a'afiaga sili ona taatele o le oral doxycycline hydrochloride i taifau ma pusi o le pua'i, manava manava, ma le fa'aitiitia o le fia'ai. Ina ia faʻaitiitia faʻafitauli leaga, e leai se faʻaititia tele o le faʻaaogaina o vailaʻau na matauina pe a inu ma meaʻai. 40% o maile na maua togafitiga na faʻaalia ai le faʻateleina o enzymes e fesoʻotaʻi ma le ate (alanine aminotransferase, alkaline phosphatase). Ole taua ole fa'amanino ole fa'atuputeleina ole gaioiga ole ate e le'o manino.